Hi Andy, 
This is not a built-in feature but you could write a TypeConverter to use it in the fields you want. I was curious about this type (I never used it before) so I gave it a try writing my own converter. I could assign it to fields, generate code, fetch an entity and save it back. The protected field was Customer.Phone. I was able to fetch the data from DB, while the field is not readable in the code, and then set it to a new value using the underlying converter using InteropServices.Marshal.SecureStringToGlobalAllocUnicode(value). 
The TypeConverter, a test .llblgenproj file and a Test .net project zipped and attached to this message. Maybe it helps. To use it:
- Compile the NWTC.TypeConverters project. 
- Copy the compiled NWTC.TypeConverters.dll to [LLBLGen Installation Folder]\TypeConverters
- Copy the NWTC.TypeConverters.typeimports file (it's in the root of the zipped folder) into [LLBLGen Installation Folder]\TypeConverters folder. 
- Open the file used in (3) and validate that the path to the LLBLGen installation folder is ok. 
- Now you can use it. There is a LLBLGen project and a solution to test. 
Useful links:
- Type shorcuts
- How to automatically assign Type Converters.
- Type Import Definitions
Now that I made that spike test, I really don't know whether or not this is 100% useful for what you are looking for. I see that ADO.Net doesn't support this type directly. It's used typically for protect the SQLCredentials in a connection string, but not for data types in ADO.Net. So, at some point, just before the conversion from the data coming from DB and the entity initialization, there is a string in plain text that is transformed into a SecureString by the converter at Entity initialization. 
So, for a moment that plain string was in the memory, right?
How would you do it if you just have a ADO.Net connection and want to protect some field of the resulset?
								
								
									Attachments
									
										
											| Filename | File size | Added on | Approval | 
									
									
											
												| NWTC.zip | 48,157 | 31-Oct-2018 08:04.04 | Approved |